hpci improves reproducibility of computational biology research by integrating Continuous Integration with High Performance Computing clusters.

hpci enhances reproducibility in computational biology by integrating CI platforms with HPC clusters, demonstrating utility across five workflows.

• Why it matters: Reproducibility issues hinder progress in bioinformatics, and existing CI solutions are limited by platform dependency and administrative requirements, restricting widespread adoption.
• What they did: The authors developed hpci, an open-source, platform-agnostic utility that connects CI systems like GitHub Actions and GitLab CI with HPC schedulers such as Slurm and PBS, operating as a standard unprivileged user via SSH without cluster-side installation, and providing feedback through exit codes.
• The result: hpci's implementation across diverse workflows shows its effectiveness in automated testing and continuous analysis, supporting reproducibility verification in bioinformatics research.