PanGBank: a large-scale resource of precomputed microbial pangenomes built with PPanGGOLiN.

PanGBank provides precomputed pangenomes for over 4,600 prokaryotic species, covering more than 393,000 genomes, enabling large-scale microbial comparative genomics.

• Why it matters: Understanding microbial diversity and genome evolution requires accessible, standardized, and comprehensive resources; current tools lack large-scale, integrated pangenome data at this level.
• What they did: The database was built using PPanGGOLiN to generate graph-based pangenomes, including gene families, regions of plasticity, and functional modules, with multiple access options.
• The result: PanGBank facilitates exploration of microbial diversity and adaptive traits, exemplified by analyzing antimicrobial resistance in Acinetobacter baumannii, advancing research in microbial genomics.