Nature Cancer · 1 Oct 2026 · Journal Article

A breakthrough in p53-targeted therapy.

Wiman

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CDK2 Inhibition Exerts RB-Independent Antitumor Activity in CDK4/6 Inhibitor-Resistant HR+/HER2- Breast Cancer.
Cancer Research · 2 Oct 2026 · Journal Article
CDK2 inhibitors induce RB-independent tumor suppression in CDK4/6 inhibitor-resistant HR+/HER2- breast cancer, with disease stabilization observed in patients.
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https://jclub.com.au/a/42391342
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MDM2 P1/P2 promoter usage separates autonomously proliferative and environment-adaptive, gastric-metaplastic programs in colorectal cancer
bioRxiv · 29 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.753357
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Extended role of p21 during the exit from p21-induced G0/G1 arrest
bioRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.12.23.630045
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