bioRxiv · 21 Sept 2026 · Preprint · Open access

Extended role of p21 during the exit from p21-induced G0/G1 arrest

Zheng, Ai + 7 more

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CDK2 Inhibition Exerts RB-Independent Antitumor Activity in CDK4/6 Inhibitor-Resistant HR+/HER2- Breast Cancer.
Cancer Research · 2 Oct 2026 · Journal Article
CDK2 inhibitors induce RB-independent tumor suppression in CDK4/6 inhibitor-resistant HR+/HER2- breast cancer, with disease stabilization observed in patients.
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A breakthrough in p53-targeted therapy.
Nature Cancer · 1 Oct 2026 · Journal Article
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MDM2 P1/P2 promoter usage separates autonomously proliferative and environment-adaptive, gastric-metaplastic programs in colorectal cancer
bioRxiv · 29 Sept 2026 · Preprint
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