Environmental pollution · 15 Sept 2026 · Journal Article

Triphenyl phosphate exacerbates lung cancer metastasis by activating NF-κB signaling pathway.

Shi, Zong + more

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ABTB1, as an E3 ubiquitin ligase, suppresses Th17 cell differentiation and mitigates autoimmune inflammation by promoting STAT3 ubiquitination and degradation.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
ABTB1 functions as an E3 ubiquitin ligase that suppresses Th17 cell differentiation by promoting STAT3 degradation, reducing autoimmune inflammation.
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Caspase-3 cleaves CYLD to restrict interferon signaling during mitochondrial apoptosis.
EMBO Reports · 1 Sept 2026 · Journal Article
Caspase-3 cleaves CYLD at a novel site to limit interferon signaling during mitochondrial apoptosis, reducing inflammation and promoting immune silence.
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Blockade of Tumor TAK1 Induces DNA Damage and Immunogenic cGAS-STING Pathway Activation in Pancreatic Cancer.
Gastroenterology · 1 Sept 2026 · Journal Article
Inhibiting TAK1 in pancreatic ductal adenocarcinoma enhances immune infiltration and activates DNA damage pathways, with significant effects observed in mouse models.
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