Multi-Omics Analyses Reveal the Red and Far-Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana.

Red and far-red light treatment increases heterologous GFP and taxadiene production in Nicotiana benthamiana by over 57% and 76.5%, respectively, compared to white light.

• Why it matters: Optimizing light conditions is crucial for improving plant-based production systems, yet its effects on transient expression efficiency remain poorly understood.
• What they did: Researchers applied five different light qualities to N. benthamiana, measuring GFP and taxadiene yields, and used multi-omics analyses to understand underlying mechanisms.
• The result: LED-red light creates a more favorable environment for Agrobacterium growth, boosting gene expression and metabolite accumulation, thus offering a practical tool for plant synthetic biology applications.