bioRxiv · 16 Aug 2026 · Preprint · Open access

Type I Natural Killer T Cells Suppress Infection-Induced Cytokine Storm Through an IL-22-STAT3 Axis

Torres, Setzu + 9 more

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HnRNPK limits memory B-cell and plasma cell differentiation, maintaining germinal center B-cell output by regulating transcription and metabolism.
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Monocyte-derived galectin-1(hi) cells provide innate immune help in the generation of functional memory CD8(+) T cells.
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Intratumoral T cell activation kills tumors regardless of T cell specificity.
Nature Immunology · 1 Oct 2026 · Journal Article
Intratumoral T cell activation can eradicate tumors without tumor-specific T cell receptors, relying on paracrine signaling and innate immune responses.
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https://jclub.com.au/a/42711529
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