bioRxiv · 1 Oct 2026 · Preprint · Open access

Experimentally Defined Tm-Guided Exon Exon Junction Primer Design Enables Specific Discrimination of Highly Similar RNA Variants

Ahn, Lee + 2 more

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Familial Parkinson's Disease Mutations Converge on Alternative Splicing Programs Linked to Lysosomal, Autophagic and Vesicle Trafficking Pathways
bioRxiv · 1 Oct 2026 · Preprint
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- 2 cites
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https://jclub.com.au/a/10.1101/2024.02.28.582420
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Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
Plakophilin 1 (PKP1) suppresses keratinocyte innate immune responses by sequestering RNA helicases, preventing excessive inflammation in healthy skin cells.
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https://jclub.com.au/a/42618693
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NCBP1 stress signaling drives alternative S6K1 splicing inhibiting translation.
Nature Chemical Biology · 1 Oct 2026 · Journal Article
Nuclear stress-induced modification of NCBP1 at cysteine 436 causes alternative splicing of over 250 genes, including S6 kinase, leading to translation inhibition.
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https://jclub.com.au/a/41667655
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