bioRxiv · 12 Aug 2026 · Preprint · Open access

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

Xu, Gonepudi + 13 more

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Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization.
eLife · 2 Oct 2026 · Journal Article
Gp41-directed antibodies neutralize HIV-1 by allosterically stabilizing or opening Env conformations, revealing two distinct modes of neutralization with long-range effects.
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Mechanisms of HIV-1 assembly, release and maturation.
Nature Reviews Microbiology · 1 Oct 2026 · Review
Advances in structural biology and imaging have revealed detailed mechanisms of HIV-1 assembly, release, and maturation, enabling targeted antiviral development.
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Finishing the fight against HIV.
Nature Microbiology · 29 Sept 2026 · Editorial
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https://jclub.com.au/a/42811104
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