bioRxiv · 17 Sept 2026 · Preprint · Open access

Structural basis of context-dependent RORγt target gene activation on chromatin

Strutzenberg, Li + 13 more

Open access

Abstract ↗AI briefThe abstract is read at the publisher; the brief is JClub's.

The AI brief for this paper is being written. Open it in JClub to read the paper with the brief as soon as it lands.

Read the brief in JClub →

Neutrophil-Driven Trogocytosis in Pancreatic Ductal Adenocarcinoma Liver Metastases Restrains Immunosuppressive Macrophage Polarization and Limits Metastatic Progression.
Gastroenterology · 1 Oct 2026 · Journal Article
Neutrophils limit immunosuppressive macrophage polarization in PDAC liver metastases through trogocytosis, reducing metastatic progression by 50%.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42102979
Open in JClub
Neutrophil-integrated syncytial CAR macrophage for cancer immunotherapy.
Nature Immunology · 1 Oct 2026 · Journal Article
Neutrophil-integrated syncytial CAR macrophages significantly enhance tumor infiltration and therapeutic efficacy, reducing tumor burden and preventing recurrence in mouse models.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42613461
Open in JClub
Reactive oxygen species stimulate Paneth cell plasticity and diminish antimicrobial function.
EMBO Journal · 1 Oct 2026 · Journal Article
Elevated reactive oxygen species induce Paneth cell dedifferentiation and reduce antimicrobial function, impairing intestinal innate immunity during inflammation.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42471443
Open in JClub

Journals this month

All journals →

Moving areas, week to 3 Oct 2026

All research areas →

Read