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Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma

bioRxiv · 8 Oct 2026 · Preprint · Open access

Woodruff, Bailey + 14 more

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IL-1α Expands SLC2A1highSPP1highIFNlow Myeloid Cells to Drive Immune Escape and Malignant Transformation of Precancers.
Cancer Research · 2 Oct 2026 · Journal Article
IL-1α promotes expansion of SLC2A1highSPP1highIFNlow myeloid cells that drive immune escape and malignant transformation in precancerous head and neck lesions.
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https://jclub.com.au/a/42446924
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Macrophage-Induced Senescent Cancer-Associated Fibroblasts Promote SASP-Mediated Chemoresistance in Colorectal Cancer.
Cancer Research · 2 Oct 2026 · Journal Article
Macrophage-induced IL1B-IL1R1 signaling promotes senescent CAFs that mediate chemoresistance in colorectal cancer.
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https://jclub.com.au/a/42418705
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GM-CSF Programs Alveolar Macrophages to Maintain Pulmonary Lymphocyte Homeostasis
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.28.753165
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