Programmable methylation engineering enables scalable biosynthesis of complex alkaloids by optimizing methyltransferase function and cofactor cycling.
Berberine and alkaloids research
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DgMYB4 regulates anthocyanin biosynthesis and modification, with its expression linked to seasonal flower color variation in Delphinium grandiflorum.
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Overexpression of AabHLH140 in Artemisia annua boosts artemisinin and polymethoxylated flavonoid levels, with transgenic Nicotiana tabacum also showing increased terpenoids.
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