AabHLH140 simultaneously enhances artemisinin and polymethoxylated flavonoid accumulation in Artemisia annua.
- Open access
Overexpression of AabHLH140 in Artemisia annua boosts artemisinin and polymethoxylated flavonoid levels, with transgenic Nicotiana tabacum also showing increased terpenoids.
- Why it matters: Enhancing multiple valuable metabolites simultaneously can improve production efficiency and reduce costs, addressing a key challenge in metabolic engineering of plants.
- What they did: Researchers characterized the transcription factor AabHLH140 and overexpressed it in A. annua and N. tabacum, observing significant increases in target metabolites.
- The result: AabHLH140 proves to be a promising genetic target for the coordinated enhancement of diverse plant metabolites, advancing strategies for metabolic engineering.