Pulmonary Hypertension Research and Treatments
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Latest in Pulmonary Hypertension Research and Treatments
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S1PR1, CA2, and ABCG2 are identified as key ion homeostasis-related genes with strong diagnostic potential for pulmonary arterial hypertension, with S1PR1 showing protective effects.
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Sotatercept reduces right ventricular contractility by 24 weeks in pulmonary arterial hypertension patients but maintains RV-PA coupling and improves overall right heart mechanics.
Pulmonary-artery denervation reduces clinical worsening by nearly 50% in patients with heart failure-related pulmonary hypertension compared to medical therapy alone.
Transcatheter tricuspid-valve repair significantly reduces death and hospitalization risks in patients with severe tricuspid regurgitation, with a win ratio of 2.42 at 1 year.
Intersectional genetics enabled precise targeting of arterial and nonvascular smooth muscle cell subtypes, revealing organ-specific gene signatures and disease responses.
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