In adults with in-hospital cardiac arrest, sodium bicarbonate vs. placebo did not increase sustained ROSC rates.

Sodium bicarbonate administration does not improve sustained return of spontaneous circulation in adults experiencing in-hospital cardiac arrest compared to placebo.

• Why it matters: Understanding effective interventions for cardiac arrest is critical to improve survival outcomes; current evidence on sodium bicarbonate's benefit remains inconclusive.
• What they did: The study compared sodium bicarbonate versus placebo in adult in-hospital cardiac arrest patients, assessing their impact on sustained ROSC rates through a controlled trial.
• The result: Findings show no significant difference in sustained ROSC rates between the two groups, suggesting sodium bicarbonate may not enhance resuscitation success in this setting.