Brain cognition gaps reveal associations with dopamine and factors related to brain health through artificial intelligence prediction of functional connectome.

Deep learning reveals that brain connectomes during tasks, especially movie-watching, predict individual cognitive differences with up to 80% accuracy in Homo sapiens.

• Why it matters: Understanding how brain function relates to cognition is crucial for identifying vulnerabilities and resilience factors, yet optimal brain states for prediction remain unclear.
• What they did: Researchers used a deep learning model to analyze functional connectomes during resting, movie-watching, and n-back tasks, focusing on episodic and working memory performance in humans.
• The result: Findings show task-based connectomes, notably during movie-watching, effectively predict cognition, and the brain cognition gap correlates with dopamine levels and health factors, offering insights into brain resilience.