Harnessing Yeast Biodiversity for Advanced Industrial Applications.

Harnessing yeast biodiversity, including diverse natural and engineered strains, advances industrial bioproduction with over 100 strain libraries and extremophilic models.

• Why it matters: Understanding and utilizing yeast biodiversity addresses the need for more efficient, sustainable, and versatile bioproduction systems in pharmaceuticals, biofuels, and biomaterials.
• What they did: The review covers recent progress in exploiting natural diversity from ecological adaptation and genetic variation, as well as artificial diversity through laboratory evolution, engineering, and synthetic biology, supported by multi-omics and AI tools.
• The result: This integrated approach enables optimized strain development and process strategies, unlocking the full potential of yeast biodiversity for innovative and efficient industrial applications.