Geometric constraints on the architecture of mammalian cortical connectomes.

A simple geometric model explains the complex, conserved architecture of mammalian cortical connectomes across multiple species and scales.

• Why it matters: Understanding how cortical connectomes develop their intricate topology is crucial for insights into brain function and evolution, yet the underlying principles remain unclear.
• What they did: Researchers developed an analytical model based on neural field theory that emphasizes physical constraints and resonant geometric modes, comparing it to existing methods across various species and imaging techniques.
• The result: The model accurately reproduces key topological and topographical features of cortical connectomes, highlighting geometry's fundamental role in shaping brain networks over 90 million years of evolution.