Immunity · 11 Aug 2026 · Journal Article · Open access

A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state.

Yang, Huang + more

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IL-17D reprograms CD93(+) antigen-presenting cells in the glioblastoma microenvironment.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
IL-17D reprograms CD93(+) antigen-presenting cells in glioblastoma, extending survival by substantial reorganization of the tumor immune environment.
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Refining therapeutic targeting of interleukin-6 by signalling mode selectivity.
Nature Reviews Drug Discovery · 23 Sept 2026 · Review
Selective targeting of IL-6 trans-signalling pathway offers potential for safer, more precise therapies, as it accounts for distinct roles in disease and homeostasis.
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A cell-intrinsic steroidogenic checkpoint constrains female Th2 effector output independently of gonadal hormones
bioRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.13.724806
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