Gastroenterology · 1 Sept 2026 · Journal Article

Primary Immunodeficiencies Masquerading as Inflammatory Bowel Diseases.

Fonseca, Noor

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ABTB1, as an E3 ubiquitin ligase, suppresses Th17 cell differentiation and mitigates autoimmune inflammation by promoting STAT3 ubiquitination and degradation.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
ABTB1 functions as an E3 ubiquitin ligase that suppresses Th17 cell differentiation by promoting STAT3 degradation, reducing autoimmune inflammation.
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Obexelimab and the Promise of Nondepleting B-Cell Therapy in IgG4-Related Disease.
New England Journal of Medicine · 1 Oct 2026 · Editorial
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Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity.
Nature · 30 Sept 2026 · Journal Article
Loss of histone readers MLLT1 and MLLT3 eliminates all AID-dependent mutagenic activity, highlighting their essential role in locus-specific antibody diversification.
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