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Ebola virus transmission among healthcare workers: genomic epidemiological analysis of the 2014 Kenema Government Hospital outbreak
medRxiv · · Preprint · Open access
Shin, Momoh + 16 more
Abstract ↗AI summary
The abstract is read at the publisher; the summary is JClub's.
Healthcare worker infections at Kenema Government Hospital in Sierra Leone were linked to healthcare worker-to-healthcare worker transmission, with 22 candidate links exceeding a 5% posterior threshold.
- Why it matters: In 2014, many healthcare worker infections disrupted care, but it was unclear whether they mainly came from repeated patient exposure or from colleague transmission under capacity constraints.
- What they did: The team analyzed 279 Ebola virus genomes from Kenema District, including 35 from infected healthcare workers, using Bayesian transmission inference with juniper and expanded surveillance plus staff accounts.
- The result: Healthcare workers made up 33.2% of expected onward transmissions at their peak in the two-week window beginning June 23, 2014, supporting interconnected workforce spread across wards and departments.
The findingWhy it mattersWhat they didThe result
- Open access