bioRxiv · 26 Aug 2026 · Preprint · Open access

Donor-derived CD8+CD122+ Tregs generated in mixed donor chimeric NOD mice suppress autoreactive T cells

Pathak, Bader + 20 more

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MARCH2/3 target FcγRI for K27-linked polyubiquitination and degradation to restrict the inflammatory response.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
MARCH2 and MARCH3 redundantly target FcγRI for K27-linked polyubiquitination and degradation, limiting inflammatory responses and disease severity.
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Metabolic switch: lymphocytes and the onset of T-cell-mediated autoimmunity.
Cellular & molecular immunology · 1 Oct 2026 · Review
Metabolic reprogramming in lymphocytes, including increased glycolysis and mitochondrial dysfunction, drives T-cell-mediated autoimmunity in diseases like MS, RA, and T1D.
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The ISChip: A high-throughput qPCR array for absolute quantification of insertion sequences across the One Health continuum.
Environmental pollution · 1 Oct 2026 · Journal Article
ISChip enables absolute quantification of 183 insertion sequences across diverse environmental samples with high sensitivity, revealing key hotspots in the One Health continuum.
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https://jclub.com.au/a/42349820
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