bioRxiv · 28 Sept 2026 · Preprint · Open access

NAD+ Replenishment Reduces Cardiomyocyte Senescence and Improves Diastolic Function in the Aged Male Heart

Huang, Wang + 9 more

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2 cites

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Condensate-driven triglyceride reduction links α-synuclein to mitochondrial dysfunction.
EMBO Reports · 29 Sept 2026 · Journal Article
α-Synuclein reduces triglyceride levels and disrupts lipid droplet and mitochondrial structure, linking lipid metabolism to neurodegenerative toxicity in C. elegans.
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NLP-12/Cholecystokinin signaling stabilizes sensory dendritic structure and protects neuronal healthspan in Caenorhabditis elegans
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.05.709874
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NAD(+) depletion by catalytic TIR domains triggers a distinct form of regulated necrosis in mammalian cells.
Proceedings of the National Academy of Sciences · 22 Sept 2026 · Journal Article
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https://jclub.com.au/a/42752230
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