bioRxiv · 10 Sept 2026 · Preprint · Open access

L-type calcium channels link oxidative stress to calcium signaling pathway and membrane excitability: Insights from computational modeling of dopaminergic neurons

Andres, Karratti-Abordo + 4 more

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Zinc is a key regulator of the sperm-specific K(+) channel (Slo3) function.
eLife · 30 Sept 2026 · Journal Article
Intracellular zinc directly inhibits the sperm-specific Slo3 potassium channel by up to micromolar concentrations, with slow dissociation dynamics, affecting sperm capacitation.
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Computational Framework for Identifying Ion Channel Mutation-Compensating Interventions
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.20.753002
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Presynaptic Ca(V)2.1 calcium-dependent facilitation enables reliable auditory information transfer.
Cell Reports · 22 Sept 2026 · Journal Article
Ca V 2.1 calcium-dependent facilitation is essential for reliable auditory information transfer, with a 37% reduction in postsynaptic firing precision when absent.
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