From Hippocrates to Biologics, The Evolving History of Pericarditis: A Review.

Advances in imaging, targeted therapies, and understanding autoinflammatory mechanisms have transformed pericarditis management from symptom control to personalized, mechanism-based care.

• Why it matters: Pericarditis remains a common cardiovascular condition with evolving diagnosis and treatment, highlighting the need for improved strategies to reduce recurrence and improve outcomes.
• What they did: The review traces the historical progression from early clinical descriptions to modern techniques, including echocardiography, cardiac magnetic resonance imaging, and randomized trials of therapies like colchicine and interleukin-1 inhibitors, involving key developments over centuries.
• The result: These advances enable more accurate diagnosis, personalized treatment, and better long-term management, paving the way for future innovations in understanding and treating pericardial disease.