A consensus-based guideline for personalized bacteriophage therapy.

A consensus-based guideline with over 60 recommendations standardizes personalized bacteriophage therapy, facilitating safe and effective clinical implementation worldwide.

• Why it matters: The lack of clear principles, procedures, and quality standards hampers the safe, transparent, and regulated use of phage therapy, limiting its potential for treating resistant bacterial infections.
• What they did: Developed through a collaborative effort involving 20 professional societies, patient groups, and 18 international experts, the guideline addresses core principles, infrastructure, quality control, administration, and future research needs.
• The result: This comprehensive, practice-oriented framework enables safer, more consistent application of phage therapy, supporting regulatory oversight and guiding future research to advance clinical use.