Liver transplantation for primary liver cancers in the era of transplant oncology.
Liver transplantation offers a highly effective curative option for primary liver cancers, with expanded eligibility through neoadjuvant strategies and biomarker-guided selection.
- Why it matters: Optimizing patient selection and management is crucial to improve outcomes and expand transplant access for patients with advanced liver tumors, addressing current limitations in treatment options.
- What they did: The study reviews the multi-step process of liver transplantation, including neoadjuvant therapies, immunosuppression management, and emerging biomarkers like circulating tumor DNA and microRNAs, to refine candidate selection and post-transplant monitoring.
- The result: Implementing these approaches can enhance personalized treatment, improve survival rates, and enable earlier detection of recurrence, advancing transplant oncology for primary liver cancers.