A wireless modular platform for neuro-behavioral recording and closed-loop manipulation in small animals.
WILD, a lightweight wireless platform with real-time closed-loop capabilities, enables long-term multimodal neural and behavioral recordings in freely moving mice.
- Why it matters: Understanding naturalistic social behaviors in small animals is limited by current tethered or constrained wireless systems, hindering insights into neural mechanisms.
- What they did: The team developed WILD, integrating neural probes, optogenetics, sensors, and a camera into a compact device, capable of detecting neural events and behavioral motifs for closed-loop interventions.
- The result: This platform allows comprehensive, long-term study of neural activity, locomotion, vocalizations, and eye movements in natural settings, advancing research into the neural basis of complex behaviors.