Nature Communications · 4 Sept 2026 · Journal Article · Open access

Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity.

Gilioli, Fusco + more

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Macrophage-Induced Senescent Cancer-Associated Fibroblasts Promote SASP-Mediated Chemoresistance in Colorectal Cancer.
Cancer Research · 2 Oct 2026 · Journal Article
Macrophage-induced senescent cancer-associated fibroblasts drive 78% chemoresistance in colorectal cancer via SASP factors IL6 and CXCL12.
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Blood cell composition reveals distinct biological interpretation of DNA methylation age and age acceleration.
Genome Medicine · 2 Oct 2026 · Journal Article
Blood cell composition accounts for up to 53% of variation in DNA methylation age, with distinct influences on epigenetic clock measures and biological processes.
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Single-stranded telomeric repeats segregate into spatial compartments within ALT-associated PML bodies
bioRxiv · 30 Sept 2026 · Preprint
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