First draft genome sequence of the emerging sexually transmitted dermatophyte Trichophyton mentagrophytes genotype VII.
Whole-genome sequencing reveals that Trichophyton mentagrophytes genotype VII forms a highly clonal, distinct population causing sexually transmitted dermatophytosis.
- Why it matters: Understanding the genetic makeup of this emerging pathogen is crucial for developing targeted prevention and control strategies for sexually transmitted skin infections.
- What they did: Four TMVII isolates from UK patients diagnosed between 2021 and 2025 were sequenced and analyzed alongside related strains from animals and other genotypes, using whole-genome sequencing and SNP-based phylogenetics.
- The result: The study shows TMVII strains are highly genetically similar and separate from zoophilic and other anthropophilic T. mentagrophytes, aiding in epidemiological tracking and intervention efforts.