Imaging the hallmarks of cancer.

Non-invasive imaging of cancer hallmarks enables real-time monitoring and stratification of tumors, with some techniques already impacting clinical treatment decisions.

• Why it matters: Understanding and tracking tumor heterogeneity and mutation-driven evasion are critical for improving personalized cancer therapies and outcomes.
• What they did: The review discusses various imaging methods, including biomolecule-targeted probes and indirect approaches, enhanced by AI techniques like radiomics and deep learning, evaluated in clinical contexts.
• The result: These imaging strategies facilitate better treatment guidance and patient stratification, advancing precision medicine and enabling dynamic assessment of tumor biology.