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ImmunityJClubProgranulin deficiency-induced lysosomal dysfunction drives maladaptive myeloid cell states through the MITF/TFE transcription factors.Immunity · 11 Aug 2026 · Journal ArticleProgranulin deficiency causes lysosomal dysfunction that triggers maladaptive myeloid cell states via MITF/TFE transcription factors, impacting neurodegeneration.3 citesOpenShareCopy linkPost on XPost on BlueskyShare on LinkedInhttps://jclub.com.au/a/42546695Open in JClub