bioRxivJClubAn Itch Receptor Drives MelanomabioRxiv · 20 Sept 2026 · Preprint · Open accessAn Itch Receptor Drives MelanomaGour, Atakkatan + 11 moreOpen accessAbstract ↗AI briefThe abstract is read at the publisher; the brief is JClub's.The AI brief for this paper is being written. Open it in JClub to read the paper with the brief as soon as it lands.Read the brief in JClub →Related in JClubNat Chem BiolJClubDevelopment of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment.Nature Chemical Biology · 1 Oct 2026 · Journal ArticleA novel small-molecule inverse agonist, HEP-50768, effectively targets MRGPRX4 and suppresses cholestatic itch in preclinical models.1 citesOpenShareCopy linkPost on XPost on BlueskyShare on LinkedInhttps://jclub.com.au/a/41957282Open in JClub
Nat Chem BiolJClubDevelopment of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment.Nature Chemical Biology · 1 Oct 2026 · Journal ArticleA novel small-molecule inverse agonist, HEP-50768, effectively targets MRGPRX4 and suppresses cholestatic itch in preclinical models.1 citesOpenShareCopy linkPost on XPost on BlueskyShare on LinkedInhttps://jclub.com.au/a/41957282Open in JClub