medRxiv · 2 Sept 2026 · Preprint · Open access

The Cartilage Thickness Score (CTh-Score) detects a structural effect of 2-year weight loss: data from the Osteoarthritis Initiative

Margain, Favre + 2 more

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1 cites

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Articular calcified cartilage microarchitecture has a predictive role in abnormal osteochondral strain distributions in murine age-related osteoarthritis
bioRxiv · 25 Sept 2026 · Preprint
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The gene-regulatory evolution of the human skeleton.
Nature · 23 Sept 2026 · Journal Article
Gene-regulatory changes in over 15,000 loci drove extensive remodeling of the human skeletal extracellular matrix, including a three-to-fourfold reduction in joint GAG content.
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Targeting pro-senescent PTGS2(+) macrophages alleviates chondrocyte senescence and osteoarthritis progression.
Cell Reports · 22 Sept 2026 · Journal Article
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