bioRxiv · 10 Sept 2026 · Preprint · Open access

Loss of Sarm1 Mitigates Axonal and Neuronal Degeneration and Promotes Neuronal Repair After Ischemic Stroke

Wang, An + 8 more

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2 cites

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Allele-Specific Mechanisms Guide Salvage Therapy to Overcome Daraxonrasib Resistance in Pancreatic Cancer.
Cancer Research · 30 Sept 2026 · Journal Article
KRASG12R pancreatic cancer cells develop resistance to daraxonrasib via EGFR/RASWT signaling, enabling effective trametinib-based therapy and extending patient survival to 40 months.
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High-throughput screening and structure-guided design of small molecules enable modulation of SAL-PAP stress signaling.
Journal of Experimental Botany · 29 Sept 2026 · Journal Article
Small molecule V20 inhibits SAL phosphatase activity, increasing PAP levels and stress tolerance in Arabidopsis thaliana with 3-fold greater potency than existing inhibitors.
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Divergent contributions of multiple PPIases to cell survival, sociality, and stress tolerance in Myxococcus xanthus DK1622.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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