Research area · week to 3 Oct 2026

Estrogen and related hormone effects

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Switching to camizestrant at ESR1 mutation emergence before disease progression during first-line treatment of hormone receptor-positive advanced breast cancer (SERENA-6): extended analysis of a double-blind, placebo-controlled, randomised, phase 3 trial.
The Lancet Oncology · 1 Aug 2026 · Journal Article
Switching to camizestrant at ESR1 mutation emergence during first-line therapy significantly extends progression-free survival in hormone receptor-positive advanced breast cancer, with a median of 16.8 months.
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https://jclub.com.au/a/42442380
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Aryl hydrocarbon receptor activation by imidacloprid as a promoter of HER2(+) breast cancer progression: In silico, in vitro and in vivo studies.
Environmental research · 1 Oct 2026 · Journal Article
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https://jclub.com.au/a/42595034
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QuantiTrack: A unified software to study protein dynamics in living cells
bioRxiv · 15 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.19.706877
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Estriol is a Stronger Transcriptional Activator than is either 17beta-Estradiol or Estrone of Hu-man and Elephant Shark Estrogen Receptor-alpha and Estrogen Receptor-beta transfected into COS-7 Cells
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.03.736429
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Mass Spectrometry-Based Profiling of Deuterium-Labeled Sex Steroids Enables Non-Invasive Mapping of Steroid Dynamics in Intact Mice
bioRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.16.694587
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Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer.
Genome Research · 1 Sept 2026 · Journal Article
Genomic features controlling ESR1 binding and activity differ between endometrial and breast cancer, with SOX17 uniquely regulating ESR1 in endometrial cancer.
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Drug-induced nuclear cathepsin L (nCTSL) defines a targetable DNA damage response axis and PARP inhibitor sensitivity in ovarian cancer
bioRxiv · 26 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.01.09.632284
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Moved this week

Switching to camizestrant at ESR1 mutation emergence before disease progression during first-line treatment of hormone receptor-positive advanced breast cancer (SERENA-6): extended analysis of a double-blind, placebo-controlled, randomised, phase 3 trial.

Latest in Estrogen and related hormone effects

Aryl hydrocarbon receptor activation by imidacloprid as a promoter of HER2(+) breast cancer progression: In silico, in vitro and in vivo studies.

QuantiTrack: A unified software to study protein dynamics in living cells

Estriol is a Stronger Transcriptional Activator than is either 17beta-Estradiol or Estrone of Hu-man and Elephant Shark Estrogen Receptor-alpha and Estrogen Receptor-beta transfected into COS-7 Cells

Mass Spectrometry-Based Profiling of Deuterium-Labeled Sex Steroids Enables Non-Invasive Mapping of Steroid Dynamics in Intact Mice

Identification of genomic features that uniquely impact estrogen receptor alpha binding and its effects on gene expression in endometrial cancer.

Drug-induced nuclear cathepsin L (nCTSL) defines a targetable DNA damage response axis and PARP inhibitor sensitivity in ovarian cancer

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