Prediction Utility of Urinary Albumin-Creatinine vs Protein-Creatinine Ratios in Chronic Kidney Disease.

Urinary albumin-creatinine ratio (UACR) outperforms protein-creatinine ratio (UPCR) in predicting kidney failure and cardiovascular outcomes in CKD patients.

• Why it matters: Accurate prediction tools are essential for managing CKD progression and preventing adverse events, but the relative utility of UACR versus UPCR remains unclear.
• What they did: The study analyzed data from an established CKD cohort, comparing UACR and UPCR for their ability to forecast kidney failure, CKD progression, and cardiovascular events.
• The result: Findings suggest UACR provides superior predictive value, supporting its use as a key biomarker for risk stratification and clinical decision-making in CKD management.