The Gabriella Miller Kids First Data Resource for genomic research in pediatric cancer and congenital anomalies.

The Gabriella Miller Kids First Data Resource has enabled genomic research on over 30,000 pediatric patients, leading to significant breakthroughs in childhood cancer and congenital anomalies.

• Why it matters: Understanding the genetic basis of pediatric conditions is crucial for developing targeted treatments, but limited data resources have hindered progress in this field.
• What they did: The program collected and annotated genomic, demographic, and clinical data from more than 30,000 participants, providing a web-based platform for secondary research and analysis.
• The result: This resource has facilitated key discoveries in pediatric disease biology and will expand with new modalities, supporting ongoing efforts to improve outcomes for children like Gabriella Miller.