Advancing the relevance of clinical trials for older patients.

Implementing inclusive clinical trial strategies can improve relevance for older patients, with successful approaches now demonstrating feasibility and real-world applicability.

• Why it matters: Older patients are the fastest-growing group in clinical care, yet evidence guiding their treatment remains limited due to underrepresentation in trials, risking less effective care.
• What they did: The review synthesizes best practices and successful strategies, including patient selection, intervention choices, and outcome measures, supported by recent implementation successes and observational data.
• The result: Adopting these approaches enables more inclusive, relevant trials that better inform treatment decisions for older adults, ultimately enhancing clinical care and health outcomes.