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Lean, mean, breast cancer-fighting machine.

Nature Reviews Cancer · 16 Oct 2026 · Journal Article

Brewer

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JAK-STAT pathway heterogeneity governs immunotherapy response in breast cancer.
eLife · 13 Oct 2026 · Journal Article
High JAK-STAT pathway activity in breast cancer correlates with improved immunotherapy response, especially in triple-negative breast cancer patients, serving as a predictive biomarker.
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Cellular, chromatin-accessibility, and spatial contextualization of bulk transcriptional patterns linked to positive peritoneal cytology in endometrial cancer.
Frontiers in Genetics · 29 Sept 2026 · Journal Article
PPC-positive endometrial cancers are linked to increased stromal/mesenchymal activity and decreased cytotoxic/antigen-presentation transcriptional programs, correlating with poorer outcomes.
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https://jclub.com.au/a/42871041
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Metabolic programs associated with GDSC2-inferred oxaliplatin sensitivity are favorably prognostic in gastric cancer: transcriptomic and single-cell evidence.
Frontiers in Genetics · 23 Sept 2026 · Journal Article
GDSC2-inferred oxaliplatin resistance in gastric cancer is linked to increased glycolytic and oxidative metabolic programs, with these features showing favorable or neutral prognostic associations.
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https://jclub.com.au/a/42841136
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