Antifungal drug resistance in Candida auris: molecular mechanisms and emerging therapeutic approaches.
Candida auris exhibits high multidrug resistance, complicating treatment and causing global healthcare outbreaks, with resistance mechanisms still being unraveled.
- Why it matters: Understanding the molecular basis of antifungal resistance in C. auris is critical for improving clinical management and developing effective therapies against this emerging pathogen.
- What they did: The review synthesizes current knowledge on C. auris, detailing mechanisms of resistance and recent advances in antifungal drug discovery and therapeutic strategies.
- The result: This work highlights key resistance pathways and innovative approaches, paving the way for improved treatments and containment of C. auris infections worldwide.